The former Denham Film Studios operated from 1936 and pictures shot there included Brief Encounter, The Great Escape, Eyes Wide Shut, as well several James Bond films.
Later, it became known for recording film scores, including for Star Wars and James Bond, before closing in 2014.
Weston Homes, who developed the site, said: “Weston Homes is currently in discussions with Affinity Water on this matter.”
Affinity Water said it was going to trial filtration methods by putting in a £2m pilot treatment programme, which if successful would be scaled up to a £31m treatment plant at Blackford.
Richard Emmott, the water company’s public affairs adviser, said customers would have to pay for this through their bills.
“We would like to see the introduction of a ‘polluter pays’ principle and potentially for sort of whole life costing to be introduced around products that include PFAS,” he added.
An Environment Agency spokesperson said: “We are working with Buckinghamshire Council to investigate possible sources of PFAS in the vicinity of the Blackford abstraction.
“Our monitoring programme provides an extensive picture of PFAS in the environment across England, and this evidence is informing the delivery of the government’s PFAS Plan.
