Oyster nurseries have previously been installed in Sunderland and reef deployments have taken place off the coast at Whitburn in South Tyneside.
Oysters were a large part of local culture in the 1800s, with oyster saloons in Tynemouth and specialist fish markets in South Shields.
There was also an oyster bar in Durham in 1901 and several oyster merchants in Newcastle in 1863.
The rivers trust said it would set up the nursery later in the year.
“By starting with a controlled nursery site, we can learn more about what conditions are needed for oysters to thrive, and use that knowledge to inform the next stages of restoration in the estuary,” the trust added.
