The collision involved two East Midlands Railway trains – the 4.40pm from Corby to London St Pancras and the 3.50pm Nottingham to London St Pancras, the rail operator said.
A major incident has been declared, and Bedfordshire Police are continuing to respond at the scene alongside colleagues from British Transport Police, Bedfordshire Fire and Rescue, and the East of England Ambulance Service.
A police spokesperson said: “We are asking the public to please stay away from the scene to help reduce pressure on our emergency services.
“We understand that people will be concerned about loved ones however please stay at home and do not travel to the scene of the incident.
“We’re in the process of setting up a dedicated phone line for relatives and we will update as soon as this is live.”
Deputy Chief Constable Stuart Cundy from BTP said: “We’ve declared a major incident and a significant emergency service response is ongoing. We’re working at pace to establish exactly what’s happened and will provide further information as soon as we are able to”.
“Officers from British Transport Police and Bedfordshire Police are on scene with colleagues from the local authority to assist any members of the public concerned about loved ones.”
